Core B: Probe and Pharmaceutical Optimization

Core B: Probe and Pharmaceutical Optimization

Core B, the Probe and Pharmaceutical Optimization Core,  promotes the overall Center by providing general medicinal chemistry, formulation and pharmacology support to Projects 1, 2 and 3 and by closely collaborating with Core A, the Analytical Chemistry Core.Having a core dedicated to probe and reagent design, synthesis and/or verification ensures consistency, efficacy and reproducibility across the projects. For example, Core B synthesizes the test chemical nerve agent tetramethylenedisulfotetramine (TETS) and specific mechanistic probes for the individual projects.